From Drupal 8.5 on this modules has been included in the core. It is simular to Panels...
Activate in the core.
From now on one can set the layout for the whole content type. You can choose to overrule this for each node.
Then for every node, a layout tab appears.
If you do the settings for the content type or for a node the interface is the same.
You choose the content blocks. Blocks is a confusing name... it deals with fields also. The fields have become blocks.
When setting the node layout you see the node content. When setting the content type you see dummy content.
When clicking the field content you can do the display settings. Here the image field.
and the text field...
Adding a block is also possible (eg the title block).
Conclusion.. Forget Panels... Layout Builder is the future...Display Suite has some advantages on this moment. So don't throw this one away yet...